Human T-cell leukemia virus type 1 Tax protein binds to assembled nuclear proteasomes and enhances their proteolytic activity.

Human T-cell leukemia virus type 1 Tax protein binds to assembled nuclear proteasomes and enhances their proteolytic activity.

The human T-cell leukemia virus type 1 (HTLV-1) Tax protein activates the HTLV-1 long terminal repeat and key regulatory proteins involved in inflammation, activation, and proliferation and may induce cell transformation. Tax is also the immunodominant target antigen for cytotoxic T cells in HTLV-1...

Full description

Bibliographic Details
Main Authors:	Hemelaar, J, Bex, F, Booth, B, Cerundolo, V, McMichael, A, Daenke, S
Format:	Journal article
Language:	English
Published:	2001

Similar Items

The interaction between HTLV-1 Tax protein and the proteasome
by: Hemelaar, J, et al.
Published: (2001)

Post-translational modifications of the Tax oncoprotein of human T-cell leukemia virus control cytoplasmic and nuclear steps in Tax-mediated activation of the NF-κB pathway
by: Lodewick Julie, et al.
Published: (2009-09-01)

Proteolytic activity of the proteasome is required for female insect reproduction
by: Wei Wang, et al.
Published: (2021-02-01)

Role of the proteasome and non proteasomal proteases in the generation of CTL epitopes.
by: Cerundolo, V, et al.
Published: (1998)

Identification of the Cdc48•20S Proteasome as an Ancient AAA+ Proteolytic Machine
by: Barthelme, Dominik, et al.
Published: (2014)

A Tale of Two Proteolytic Machines: Matrix Metalloproteinases and the Ubiquitin–Proteasome System in Pulmonary Fibrosis
by: Willy Roque, et al.
Published: (2020-05-01)

Lipopolysaccharide induces degradation of connexin43 in rat astrocytes via the ubiquitin-proteasome proteolytic pathway.
by: Chih-Kai Liao, et al.
Published: (2013-01-01)

Nuclear Import of Yeast Proteasomes
by: Julianne Burcoglu, et al.
Published: (2015-08-01)

Nuclear Transport of Yeast Proteasomes
by: Cordula Enenkel
Published: (2014-10-01)

Nuclear Transport of Yeast Proteasomes
by: Petra Wendler, et al.
Published: (2019-05-01)

Effects of retroviral protease inhibitors on proteasome function and processing of HIV-derived MHC class I-restricted cytotoxic T lymphocyte epitopes.
by: Kelleher, A, et al.
Published: (2001)

Plastidial starch phosphorylase in sweet potato roots is proteolytically modified by protein-protein interaction with the 20S proteasome.
by: Yi-Chen Lin, et al.
Published: (2012-01-01)

Stressing the ubiquitin-proteasome system without 20S proteolytic inhibition selectively kills cervical cancer cells.
by: Ravi K Anchoori, et al.
Published: (2011-01-01)

Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat.
by: Karl A Rodriguez, et al.
Published: (2012-01-01)

p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition
by: Senthil K Radhakrishnan, et al.
Published: (2014-01-01)

Non-proteolytic activity of 19S proteasome subunit RPT-6 regulates GATA transcription during response to infection.
by: Abiola O Olaitan, et al.
Published: (2018-09-01)

Assembly Mechanisms of Specialized Core Particles of the Proteasome
by: Minghui Bai, et al.
Published: (2014-07-01)

Phosphatase UBLCP1 controls proteasome assembly
by: Shuangwu Sun, et al.
Published: (2017-01-01)

Assembly and beyond – The structure and functions of chaperones of the proteasome
by: Prasanna Venkatraman
Published: (2016-01-01)

Nuclear Ubiquitin-Proteasome Pathways in Proteostasis Maintenance
by: Dina Franić, et al.
Published: (2021-01-01)

Loss of FBXO9 Enhances Proteasome Activity and Promotes Aggressiveness in Acute Myeloid Leukemia
by: R. Willow Hynes-Smith, et al.
Published: (2019-11-01)

Role of ran binding protein 5 in nuclear import and assembly of the influenza virus RNA polymerase complex.
by: Deng, T, et al.
Published: (2006)

A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine
by: Shanshan Li, et al.
Published: (2023-11-01)

Self-Assembled Gold Nanoparticle Molecular Probes for Detecting Proteolytic Activity
by: Mu, C. Jenny, et al.
Published: (2013)

Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding.
by: Jiro Kikuchi, et al.
Published: (2013-01-01)

Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility
by: Lewis D. Blackman, et al.
Published: (2018-05-01)

Architecture and assembly of the archaeal Cdc48*20S proteasome
by: Barthelme, Dominik, et al.
Published: (2014)

Bovine leukemia virus tax gene/Tax protein polymorphism and its relation to Enzootic Bovine Leukosis
by: Irina M. Zyrianova, et al.
Published: (2020-12-01)

Cks1 activates transcription by binding to the ubiquitylated proteasome.
by: Holic, R, et al.
Published: (2010)

AMPK regulates ESCRT-dependent microautophagy of proteasomes concomitant with proteasome storage granule assembly during glucose starvation.
by: Jianhui Li, et al.
Published: (2019-11-01)

Assembly of an Evolutionarily Conserved Alternative Proteasome Isoform in Human Cells
by: Achuth Padmanabhan, et al.
Published: (2016-03-01)

Senescent cells form nuclear foci that contain the 26S proteasome
by: Tomohiro Iriki, et al.
Published: (2023-08-01)

Generation of an immunodominant CTL epitope is affected by proteasome subunit composition and stability of the antigenic protein.
by: Gileadi, U, et al.
Published: (1999)

Attachment of Proteolytic Enzyme Inhibitors to Vascular Prosthesis—An Analysis of Binding and Antimicrobial Properties
by: Aleksandra Mordzińska-Rak, et al.
Published: (2024-02-01)

Promyelocytic leukemia nuclear body-like structures can assemble in mouse oocytes
by: Osamu Udagawa, et al.
Published: (2022-06-01)

Lactoferrin Is an Allosteric Enhancer of the Proteolytic Activity of Cathepsin G.
by: Steffen Eipper, et al.
Published: (2016-01-01)

Synergy between proteasome inhibitors and imatinib mesylate in chronic myeloid leukemia.
by: Zheng Hu, et al.
Published: (2009-01-01)

Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity
by: Aboud Mordechai, et al.
Published: (2004-08-01)

An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses.
by: André, P, et al.
Published: (1998)

Advances in Proteasome Enhancement by Small Molecules
by: Dare E. George, et al.
Published: (2021-11-01)