Variation in glucose-6-phosphate dehydrogenase activity following acute malaria

Primaquine and tafenoquine are the only licensed drugs with activity against Plasmodium vivax hypnozoites but cause haemolysis in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Malaria also causes haemolysis, leading to the replacement of older erythrocytes with low G6PD activity...

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Bibliographic Details
Main Authors: Ley, B, Alam, MS, Satyagraha, AW, Phru, CS, Thriemer, K, Tadesse, D, Shibiru, T, Hailu, A, Kibria, MG, Hossain, MS, Rahmat, H, Poespoprodjo, JR, Khan, WA, Simpson, JA, Price, RN
Format: Journal article
Language:English
Published: Public Library of Science 2022