Variation in glucose-6-phosphate dehydrogenase activity following acute malaria

Primaquine and tafenoquine are the only licensed drugs with activity against Plasmodium vivax hypnozoites but cause haemolysis in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Malaria also causes haemolysis, leading to the replacement of older erythrocytes with low G6PD activity...

ver descrição completa

Detalhes bibliográficos
Principais autores: Ley, B, Alam, MS, Satyagraha, AW, Phru, CS, Thriemer, K, Tadesse, D, Shibiru, T, Hailu, A, Kibria, MG, Hossain, MS, Rahmat, H, Poespoprodjo, JR, Khan, WA, Simpson, JA, Price, RN
Formato: Journal article
Idioma:English
Publicado em: Public Library of Science 2022