Side-chains in native and random coil protein conformations. Analysis of NMR coupling constants and chi1 torsion angle preferences.

The behaviour of amino acid side-chains in proteins in solution has been characterised by analysing NMR 3JHalphaH beta coupling constants and crystallographic chi1 torsion angles. Side-chains both in the core of native folded proteins and in situations where there is an absence of close packing incl...