Plasma efavirenz exposure, sex, and age predict virological response in HIV-infected African children.
<h4>Aim</h4> <p>To characterise the efavirenz steady-state pharmacokinetics in African children using model-based approach, quantifying demographic and genotypic effects on the drug’s disposition, and conduct simulations allowing prediction of optimised doses of efavirenz in this p...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Lippincott, Williams and Wilkins
2016
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