Sickle cell disease: new opportunities and challenges in Africa.

Sickle cell disease: new opportunities and challenges in Africa.

Sickle cell disease (SCD) is one of the most common genetic causes of illness and death in the world. This is a review of SCD in Africa, which bears the highest burden of disease. The first section provides an introduction to the molecular basis of SCD and the pathophysiological mechanism of selecte...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Makani, J, Ofori-Acquah, S, Nnodu, O, Wonkam, A, Ohene-Frempong, K
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	ScientificWorld Ltd. 2013

Míreanna comhchosúla

Sickle Cell Disease: New Opportunities and Challenges in Africa
de réir: J. Makani, et al.
Foilsithe / Cruthaithe: (2013-01-01)

Development of multi-level standards of care recommendations for sickle cell disease: Experience from SickleInAfrica
de réir: Vivian Paintsil, et al.
Foilsithe / Cruthaithe: (2023-01-01)

Sickle Cell Disease: Management options and challenges in developing countries
de réir: Daniel Ansong, et al.
Foilsithe / Cruthaithe: (2013-11-01)

S127: CONSORTIUM ON NEWBORN SCREENING IN AFRICA FOR SICKLE CELL DISEASE
de réir: O Nnodu, et al.
Foilsithe / Cruthaithe: (2022-01-01)

Stroke in sickle cell disease in Africa: case report.
de réir: Makani, J
Foilsithe / Cruthaithe: (2004)

Sickle cell disease in Africa: burden and research priorities.
de réir: Makani, J, et al.
Foilsithe / Cruthaithe: (2007)

5613401 SICKLE CELL DISEASE GENOMICS OF AFRICA (SICKLEGENAFRICA) NETWORK: QUALITATIVE INTERVIEW FINDINGS ON REASONS FOR REFUSAL OF BROAD CONSENT
de réir: J.A. Osae-Larbi, et al.
Foilsithe / Cruthaithe: (2023-04-01)

Sickle Cell Disease Genomics of Africa (SickleGenAfrica) Network: ethical framework and initial qualitative findings from community engagement in Ghana, Nigeria and Tanzania
de réir: Ellis Owusu-Dabo, et al.
Foilsithe / Cruthaithe: (2021-07-01)

Editorial: Building capacity for sickle cell disease research and healthcare
de réir: Victoria Nembaware, et al.
Foilsithe / Cruthaithe: (2023-07-01)

Transcranial doppler in sickle cell disease in Africa
de réir: Ajala-Agbo, T, et al.
Foilsithe / Cruthaithe: (2007)

Caring for Africa's sickle cell children: will we rise to the challenge?
de réir: Oron, AP, et al.
Foilsithe / Cruthaithe: (2020)

Treatment for sickle cell disease in Africa: should we invest in haematopoietic stem cell transplantation?
de réir: Gift Pule, et al.
Foilsithe / Cruthaithe: (2014-05-01)

Implementation science research for the scale-up of evidence-based interventions for sickle cell disease in africa: a commentary
de réir: Joyce Gyamfi, et al.
Foilsithe / Cruthaithe: (2021-02-01)

Enablers and barriers to newborn screening for sickle cell disease in Africa: results from a qualitative study involving programmes in six countries
de réir: Leon Tshilolo, et al.
Foilsithe / Cruthaithe: (2022-03-01)

Skills Capacity Building For Health Care Services and Research Through the Sickle Pan African Research Consortium
de réir: Obiageli Eunice Nnodu, et al.
Foilsithe / Cruthaithe: (2022-06-01)

Caring for Africa’s sickle cell children: will we rise to the challenge?
de réir: Assaf P. Oron, et al.
Foilsithe / Cruthaithe: (2020-04-01)

The future of sickle cell disease therapeutics rests in genomics
de réir: Ambroise Wonkam
Foilsithe / Cruthaithe: (2023-02-01)

Sickle Cell Disease: Genetics, Cellular and Molecular Mechanisms, and Therapies
de réir: Betty S. Pace, et al.
Foilsithe / Cruthaithe: (2012-01-01)

Spatiotemporal Dysfunction of the Vascular Permeability Barrier in Transgenic Mice with Sickle Cell Disease
de réir: Samit Ghosh, et al.
Foilsithe / Cruthaithe: (2012-01-01)

Management of sickle cell disease in the community.
de réir: Brousse, V, et al.
Foilsithe / Cruthaithe: (2014)

Hydroxyurea-Induced miRNA Expression in Sickle Cell Disease Patients in Africa
de réir: Khuthala Mnika, et al.
Foilsithe / Cruthaithe: (2019-05-01)

S129: IMPLEMENTATION OF HYDROXYUREA THERAPY FOR SICKLE CELL DISEASE ON A LARGE SCALE IN GHANA
de réir: K Ohene-Frempong, et al.
Foilsithe / Cruthaithe: (2022-01-01)

Establishing a database for sickle cell disease patient mapping and survival tracking: The sickle pan-african research consortium Nigeria example
de réir: Obiageli Nnodu, et al.
Foilsithe / Cruthaithe: (2022-11-01)

Bridging the Access Gap for Comprehensive Sickle Cell Disease Management Across Sub-Saharan Africa: Learnings for Other Global Health Interventions?
de réir: Lutz Hegemann, et al.
Foilsithe / Cruthaithe: (2023-11-01)

Sickle cell anaemia in East Africa: Preliminary results from a cohort study.
de réir: Makani, J, et al.
Foilsithe / Cruthaithe: (2006)

Building research capacity for sickle cell disease in Africa: Lessons and challenges from establishing a birth cohort in Tanzania
de réir: Siana Nkya, et al.
Foilsithe / Cruthaithe: (2022-09-01)

Oxygen Saturation in Primary Teeth of Individuals With Sickle Cell Disease and Sickle Cell Trait
de réir: Wilson EM, et al.
Foilsithe / Cruthaithe: (2022-07-01)

Spectrum of cerebral blood flow velocities measured by transcranial Doppler ultrasonography in children with sickle cell disease in Africa
de réir: Ajala-Agbo, T, et al.
Foilsithe / Cruthaithe: (2006)

Health policy for sickle cell disease in Africa: experience from Tanzania on interventions to reduce under-five mortality.
de réir: Makani, J, et al.
Foilsithe / Cruthaithe: (2015)

Using dried blood spot on HemoTypeSC™, a new frontier for newborn screening for sickle cell disease in Nigeria
de réir: Chinwe O. Okeke, et al.
Foilsithe / Cruthaithe: (2022-10-01)

Nrf2 Activation With CDDO-Methyl Promotes Beneficial and Deleterious Clinical Effects in Transgenic Mice With Sickle Cell Anemia
de réir: Chibueze A. Ihunnah, et al.
Foilsithe / Cruthaithe: (2022-05-01)

Cerebral blood flow velocities measured by transcranial Doppler ultrasonography in children with sickle cell disease in Africa.
de réir: Makani, J, et al.
Foilsithe / Cruthaithe: (2005)

Protocol for a comparative cross-sectional study on characterisation of auditory impairment in sickle cell disease and sickle cell trait and its impact on health-related quality of life in Nigeria
de réir: Obiageli Nnodu, et al.
Foilsithe / Cruthaithe: (2024-01-01)

Strengthening advanced therapy for sickle cell disease in Africa: experience from sickle cell disease centre in Dar es Salaam, Tanzania
de réir: Grace Moshi, et al.
Foilsithe / Cruthaithe: (2025-01-01)

S125: THE ROLE OF THE MICROBIOME AS A SICKLE CELL DISEASE MODIFIER: AN EXPERT REVIEW
de réir: C Oosterwyk, et al.
Foilsithe / Cruthaithe: (2022-01-01)

An observational study of children with sickle cell disease in Kilifi, Kenya.
de réir: Sadarangani, M, et al.
Foilsithe / Cruthaithe: (2009)

The role of malaria infection in morbidity and mortality in sickle cell disease in east africa: Preliminary evidence from a cohort study [MIM-JM-1200]
de réir: Makani, J, et al.
Foilsithe / Cruthaithe: (2005)

A Critical Review of Sickle Cell Disease Burden and Challenges in Sub-Saharan Africa
de réir: Adigwe OP, et al.
Foilsithe / Cruthaithe: (2023-05-01)

5593300 INVESTIGATIONS OF KIDNEY DYSFUNCTION-RELATED GENE VARIANTS IN SICKLE CELL DISEASE PATIENTS IN CAMEROON (SUB-SAHARAN AFRICA)
de réir: V.B. NGO BITOUNGUI, et al.
Foilsithe / Cruthaithe: (2023-04-01)

Sustainability of newborn screening for sickle cell disease in resource-poor countries: A systematic review.
de réir: Chinwe O Okeke, et al.
Foilsithe / Cruthaithe: (2024-01-01)