Default mode network activity and white matter integrity in healthy middle-aged ApoE4 carriers

Alzheimer’s disease (AD) is most commonly detected during old age, but the underlying neuropathologic changes likely appear decades earlier, especially among patients possessing genetic risk factors, such as the isoform E4 of the apolipoprotein E (ApoE4). In this study, we used magnetic resonance im...

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Bibliographic Details
Main Authors: Patel, K, Stevens, M, Pearlson, G, Winkler, A, Hawkins, K, Skudlarski, P, Bauer, L
Format: Journal article
Language:English
Published: Springer-Verlag 2013
Subjects: