The human low affinity Fcgamma receptors IIa, IIb, and III bind IgG with fast kinetics and distinct thermodynamic properties.

Fcgamma receptors (FcgammaRs) are expressed on all immunologically active cells. They bind the Fc portion of IgG, thereby triggering a range of immunological functions. We have used surface plasmon resonance to analyze the kinetic and thermodynamic properties of the interactions between the ectodoma...

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Bibliographic Details
Main Authors: Maenaka, K, Van Der Merwe, P, Stuart, D, Jones, E, Sondermann, P
Format: Journal article
Language:English
Published: 2001