Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction.

Although dendritic cells (DCs) are the most potent antigen-presenting cells involved in numerous physiologic and pathologic processes, little is known about the signaling pathways that regulate DC activation and antigen-presenting function. Recently, we demonstrated that nuclear factor (NF)-kappaB a...

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Bibliographic Details
Main Authors: Andreakos, E, Smith, C, Monaco, C, Brennan, F, Foxwell, B, Feldmann, M
Format: Journal article
Language:English
Published: 2003