Minimal tumor necrosis factor receptor binding protein: optimum biological activity of a truncated p55 soluble tumor necrosis factor receptor-IgG fusion protein.

We have previously demonstrated, using expressed deletion constructs, that the fourth membrane proximal cysteine-rich repeat of the p55 TNF receptor (TNF-R) is not required for binding of tumour necrosis factor-alpha (TNF) or lymphotoxin-alpha (LT; tumour necrosis factor-beta). We and others have al...

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Bibliographic Details
Main Authors: Corcoran, A, Scallon, B, Trinh, H, Chernajovsky, Y, Ghrayeb, J, Feldmann, M
Format: Journal article
Language:English
Published: 1998