RAN GTPase is a RASSF1A effector involved in controlling microtubule organization.
RASSF1A is a tumor suppressor gene that is inactivated by hypermethylation of its promoter region in most types of human cancers. The incidence of spontaneous or induced tumors is significantly higher in Rassf1a(-/-) mice than in wild-type mice, confirming the tumor suppressor function of RASSF1A. R...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2009
|