Quantitative and Qualitative Differences in the In Vivo Response of NKT Cells to Distinct α- and β-Anomeric Glycolipids

NKT cells represent a unique subset of immunoregulatory T cells that recognize glycolipid Ags presented by the MHC class I-like molecule CD1d. Because of their immunoregulatory properties, NKT cells are attractive targets for the development of immunotherapies. The prototypical NKT cell ligand alpha...

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Detalles Bibliográficos
Main Authors: Parekh, V, Singh, A, Wilson, M, Olivares-Villagómez, D, Bezbradica, J, Inazawa, H, Ehara, H, Sakai, T, Serizawa, I, Wu, L, Wang, C, Joyce, S, Van Kaer, L
Formato: Journal article
Idioma:English
Publicado: American Association of Immunologists 2004