Bactericidal activities and post-antibiotic effects of ofloxacin and ceftriaxone against drug-resistant Salmonella enterica serovar Typhi

Background The clinical response to ceftriaxone in patients with typhoid fever is significantly slower than with ofloxacin, despite infection with Salmonella enterica serovar Typhi (S. Typhi) isolates with similar susceptibilities (MIC 0.03–0.12 mg/L). The response to ofloxacin is slower if the isol...

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Bibliographic Details
Main Authors: Wain, J, Simpson, JA, Luong, TDN, To, SD, Pham, TD, Baker, S, Day, NPJ, White, NJ, Parry, CM
Format: Journal article
Language:English
Published: Oxford University Press 2021