Genomic landscape and chronological reconstruction of driver events in multiple myeloma

The multiple myeloma (MM) genome is heterogeneous and evolves through preclinical and post-diagnosis phases. Here we report a catalog and hierarchy of driver lesions using sequences from 67 MM genomes serially collected from 30 patients together with public exome datasets. Bayesian clustering define...

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Bibliographic Details
Main Authors: Maura, F, Bolli, N, Angelopoulos, N, Dawson, KJ, Leongamornlert, D, Martincorena, I, Mitchell, TJ, Fullam, A, Gonzalez, S, Szalat, R, Abascal, F, Rodriguez-Martin, B, Samur, MK, Glodzik, D, Roncador, M, Fulciniti, M, Tai, YT, Minvielle, S, Magrangeas, F, Moreau, P, Corradini, P, Anderson, KC, Tubio, JMC, Wedge, DC, Gerstung, M, Avet-Loiseau, H, Munshi, N, Campbell, PJ
Format: Journal article
Language:English
Published: Springer Nature 2019