Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity against P815 mastocytoma

DNA vaccination against cancer has become a promising strategy for inducing a specific and longlasting antitumor immunity. However, DNA vaccines fail to generate potent immune responses when used as a single therapy. To enhance their activity into the tumor, a DNA vaccine against murine P815 mastocy...

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Bibliographic Details
Main Authors: Lopes, A, Vanvarenberg, K, Kos, S, Lucas, S, Colau, D, Van Den Eynde, BJ, Préat, V, Vandermeulen, G
Format: Journal article
Published: Nature Publishing Group 2018