α+-Thalassemia protects children against disease caused by other infections as well as malaria

In the South West Pacific region, the striking geographical correlation between the frequency of α+ -thalassemia and the endemicity of Plasmodium falciparum suggests that this hemoglobinopathy provides a selective advantage against malaria. In Vanuatu, paradoxically, α+ -thalassemia increases the in...

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Bibliographic Details
Main Authors: Allen, S, O'Donnell, A, Alexander, N, Alpers, M, Peto, T, Clegg, J, Weatherall, D
Format: Journal article
Language:English
Published: 1997