Synthesis of metallo-beta-lactamase inhibitors

α-Amido trifluoromethyl alcohols and ketones were synthesised via two independent routes using the Ruppert Reagent (TMS-CF3) and shown to be inhibitors of metallo-β-lactamases.

Bibliographic Details
Main Authors: Walter, M, Adlington, R, Baldwin, J, Schofield, C
Format: Journal article
Language:English
Published: 1997