An engineered ClyA nanopore detects folded target proteins by selective external association and pore entry.
Nanopores have been used in label-free single-molecule studies, including investigations of chemical reactions, nucleic acid analysis, and applications in sensing. Biological nanopores generally perform better than artificial nanopores as sensors, but they have disadvantages including a fixed diamet...
Hauptverfasser: | , , , , , |
---|---|
Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2012
|