An engineered ClyA nanopore detects folded target proteins by selective external association and pore entry.

Nanopores have been used in label-free single-molecule studies, including investigations of chemical reactions, nucleic acid analysis, and applications in sensing. Biological nanopores generally perform better than artificial nanopores as sensors, but they have disadvantages including a fixed diamet...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Soskine, M, Biesemans, A, Moeyaert, B, Cheley, S, Bayley, H, Maglia, G
Format: Journal article
Sprache:English
Veröffentlicht: 2012