Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy.
BACKGROUND: Muscle LIM protein (MLP) is an essential nuclear regulator of myogenic differentiation. Additionally, it may act as an integrator of protein assembly of the actin-based cytoskeleton. MLP-knockout mice develop a marked cardiac hypertrophy reaction and dilated cardiomyopathy (DCM). MLP is...
Main Authors: | , , , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2003
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