Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy.
BACKGROUND: Muscle LIM protein (MLP) is an essential nuclear regulator of myogenic differentiation. Additionally, it may act as an integrator of protein assembly of the actin-based cytoskeleton. MLP-knockout mice develop a marked cardiac hypertrophy reaction and dilated cardiomyopathy (DCM). MLP is...
Główni autorzy: | Geier, C, Perrot, A, Ozcelik, C, Binner, P, Counsell, D, Hoffmann, K, Pilz, B, Martiniak, Y, Gehmlich, K, van der Ven, P, Fürst, DO, Vornwald, A, von Hodenberg, E, Nürnberg, P, Scheffold, T, Dietz, R, Osterziel, K |
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Format: | Journal article |
Język: | English |
Wydane: |
2003
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