Structure of dehydroquinate synthase reveals an active site capable of multistep catalysis.

Dehydroquinate synthase (DHQS) has long been regarded as a catalytic marvel because of its ability to perform several consecutive chemical reactions in one active site. There has been considerable debate as to whether DHQS is actively involved in all these steps, or whether several steps occur spont...

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Bibliographic Details
Main Authors: Carpenter, E, Hawkins, A, Frost, J, Brown, K
Format: Journal article
Language:English
Published: 1998