STAT1 is required to establish but not maintain interferon‐γ‐induced transcriptional memory

Exposure of human cells to interferon‐γ (IFNγ) results in a mitotically heritable yet reversible state called long‐term transcriptional memory. We previously identified the clustered GBP genes as strongly primed by IFNγ. Here, we discovered that in primed cells, both interferon‐responsive transcript...

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Bibliographic Details
Main Authors: Tehrani, SS, Mikulski, P, Abdul‐Zani, I, Mata, JF, Siwek, W, Jansen, LE
Format: Journal article
Language:English
Published: EMBO Press 2023