Hypervariable antigen genes in malaria have ancient roots.
BACKGROUND: The var genes of the human malaria parasite Plasmodium falciparum are highly polymorphic loci coding for the erythrocyte membrane proteins 1 (PfEMP1), which are responsible for the cytoaherence of P. falciparum infected red blood cells to the human vasculature. Cytoadhesion, coupled with...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
BioMed Central
2013
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