Ca(2+)-calmodulin can activate and inactivate cardiac ryanodine receptors.
BACKGROUND AND PURPOSE: Ca(2+)-calmodulin (Ca(2+)CaM) is widely accepted as an inhibitor of cardiac ryanodine receptors (RyR2); however, the effects of physiologically relevant CaM concentrations have not been fully investigated. EXPERIMENTAL APPROACH: We investigated the effects of low concentrati...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2009
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