Iminosugars counteract the downregulation of the interferon gamma receptor by dengue virus
The antiviral mechanism of action of iminosugars against many enveloped viruses is hypothesized to be a consequence of misfolding of viral N-linked glycoproteins through inhibition of host endoplasmic reticulum alpha-glucosidase enzymes. Iminosugar treatment of dengue virus (DENV) infection results...
| Hauptverfasser: | , , , , , |
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| Format: | Journal article |
| Veröffentlicht: |
Elsevier
2019
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