Anomalous dynamics of a lipid recognition protein on a membrane surface

Pleckstrin homology (PH) domains are lipid-binding modules present in peripheral membrane proteins which interact with phosphatidyl-inositol phosphates (PIPs) in cell membranes. We use multiscale molecular dynamics simulations to characterize the localization and anomalous dynamics of the DAPP1 PH d...

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Detalhes bibliográficos
Principais autores: Yamamoto, E, Kalli, A, Akimoto, T, Yasuoka, K, Sansom, M
Formato: Journal article
Publicado em: Nature Publishing Group 2015