Conserved role for the Drosophila Pax6 homolog Eyeless in differentiation and function of insulin-producing neurons.

Insulin/insulin-like growth factor (IGF) signaling constitutes an evolutionarily conserved pathway that controls growth, energy homeostasis, and longevity. In Drosophila melanogaster, key components of this pathway are the insulin-like peptides (Dilps). The major source of Dilps is a cluster of larg...

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Bibliographic Details
Main Authors: Clements, J, Hens, K, Francis, C, Schellens, A, Callaerts, P
Format: Journal article
Language:English
Published: 2008