Conserved role for the Drosophila Pax6 homolog Eyeless in differentiation and function of insulin-producing neurons.
Insulin/insulin-like growth factor (IGF) signaling constitutes an evolutionarily conserved pathway that controls growth, energy homeostasis, and longevity. In Drosophila melanogaster, key components of this pathway are the insulin-like peptides (Dilps). The major source of Dilps is a cluster of larg...
Glavni autori: | Clements, J, Hens, K, Francis, C, Schellens, A, Callaerts, P |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2008
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Slični predmeti
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Mutational analysis of the eyeless gene and phenotypic rescue reveal that an intact Eyeless protein is necessary for normal eye and brain development in Drosophila.
od: Clements, J, i dr.
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Pax6 and eye development in Arthropoda.
od: Callaerts, P, i dr.
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Glial and Neuronal Neuroglian, Semaphorin-1a and Plexin A Regulate Morphological and Functional Differentiation of Drosophila Insulin-Producing Cells
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Genome-wide analysis identifies Homothorax and Extradenticle as regulators of insulin in Drosophila Insulin-Producing cells.
od: Mattias Winant, i dr.
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Co-orthology of Pax4 and Pax6 to the fly eyeless gene: molecular phylogenetic, comparative genomic, and embryological analyses.
od: Manousaki, T, i dr.
Izdano: (2011)