Empirical assessment of the validity of the 'fundamental theorem of the HapMap' in the light of 'cryptic' tagging of multiple susceptibility loci.

Underestimation of the sample size needed to detect genetic association may occur as a result of deviations from the 'fundamental theorem of the HapMap'. A biologically plausible mechanism that might cause this deviation is 'cryptic' tagging of multiple susceptibility loci by the...

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Bibliographic Details
Main Authors: Bochdanovits, Z, Heutink, P, van der Vaart, A
Format: Journal article
Language:English
Published: 2008