Empirical assessment of the validity of the 'fundamental theorem of the HapMap' in the light of 'cryptic' tagging of multiple susceptibility loci.
Underestimation of the sample size needed to detect genetic association may occur as a result of deviations from the 'fundamental theorem of the HapMap'. A biologically plausible mechanism that might cause this deviation is 'cryptic' tagging of multiple susceptibility loci by the...
Main Authors: | Bochdanovits, Z, Heutink, P, van der Vaart, A |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2008
|
Similar Items
-
The International HapMap Project
by: Gibbs, R, et al.
Published: (2003) -
An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets.
by: Zeggini, E, et al.
Published: (2005) -
Geographical affinities of the HapMap samples.
by: Miao He, et al.
Published: (2009-01-01) -
An evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population.
Published: (2006-03-01) -
An evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population.
by: Alexandre Montpetit, et al.
Published: (2006-03-01)