Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids

Isoretronecanol and trachelantamidine (laburnine) are naturally occurring pyrrolizidine alkaloids which display potent biological activity, and as such these compounds have, in recent years, attracted significant interest from the bioorganic and synthetic communities. This review delineates both the...

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Detalhes bibliográficos
Main Authors: Brambilla, M, Davies, S, Fletcher, A, Thomson, J
Formato: Journal article
Idioma:English
Publicado em: Elsevier 2014