Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids
Isoretronecanol and trachelantamidine (laburnine) are naturally occurring pyrrolizidine alkaloids which display potent biological activity, and as such these compounds have, in recent years, attracted significant interest from the bioorganic and synthetic communities. This review delineates both the...
| Príomhchruthaitheoirí: | , , , |
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| Formáid: | Journal article |
| Teanga: | English |
| Foilsithe / Cruthaithe: |
Elsevier
2014
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| _version_ | 1826291877691785216 |
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| author | Brambilla, M Davies, S Fletcher, A Thomson, J |
| author_facet | Brambilla, M Davies, S Fletcher, A Thomson, J |
| author_sort | Brambilla, M |
| collection | OXFORD |
| description | Isoretronecanol and trachelantamidine (laburnine) are naturally occurring pyrrolizidine alkaloids which display potent biological activity, and as such these compounds have, in recent years, attracted significant interest from the bioorganic and synthetic communities. This review delineates both the asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids including isoretronecanol, trachelantamidine (laburnine) and related hydroxylated compounds. © 2014 Elsevier Ltd. All rights reserved. |
| first_indexed | 2024-03-07T03:06:05Z |
| format | Journal article |
| id | oxford-uuid:b293f37c-902f-425b-858e-4e4a2cca8a9e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:06:05Z |
| publishDate | 2014 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:b293f37c-902f-425b-858e-4e4a2cca8a9e2022-03-27T04:12:41ZAsymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloidsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b293f37c-902f-425b-858e-4e4a2cca8a9eEnglishSymplectic Elements at OxfordElsevier2014Brambilla, MDavies, SFletcher, AThomson, JIsoretronecanol and trachelantamidine (laburnine) are naturally occurring pyrrolizidine alkaloids which display potent biological activity, and as such these compounds have, in recent years, attracted significant interest from the bioorganic and synthetic communities. This review delineates both the asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids including isoretronecanol, trachelantamidine (laburnine) and related hydroxylated compounds. © 2014 Elsevier Ltd. All rights reserved. |
| spellingShingle | Brambilla, M Davies, S Fletcher, A Thomson, J Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids |
| title | Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids |
| title_full | Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids |
| title_fullStr | Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids |
| title_full_unstemmed | Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids |
| title_short | Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids |
| title_sort | asymmetric and enantiospecific syntheses of 1 hydroxymethyl pyrrolizidine alkaloids |
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