Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids

Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids

Isoretronecanol and trachelantamidine (laburnine) are naturally occurring pyrrolizidine alkaloids which display potent biological activity, and as such these compounds have, in recent years, attracted significant interest from the bioorganic and synthetic communities. This review delineates both the...

書目詳細資料
Main Authors:	Brambilla, M, Davies, S, Fletcher, A, Thomson, J
格式:	Journal article
語言:	English
出版:	Elsevier 2014

相似書籍

Asymmetric syntheses of the 1-hydroxymethyl-2-hydroxy substituted pyrrolizidines (−)-macronecine, (−)-petasinecine, (−)-1-epi-macronecine, (+)-1-epi-petasinecine and (+)-2-epi-rosmarinecine
由: Brambilla, M, et al.
出版: (2016)

Pyrrolizidines, indolizidines and quinolizidines via a double reductive cyclisation protocol: concise asymmetric syntheses of (+)-trachelanthamidine, (+)-tashiromine and (+)-epilupinine
由: Brambilla, M, et al.
出版: (2016)

Pyrrolizidine alkaloids.
由: Robertson, J, et al.
出版: (2014)

The asymmetric syntheses of pyrrolizidines, indolizidines and quinolizidines via two sequential tandem ring-closure/N-debenzylation processes.
由: Davies, S, et al.
出版: (2014)

Asymmetric syntheses of functionalized pyrrolizidin-3-ones
由: Christine Greck, et al.
出版: (2012-08-01)

Polyhydroxylated pyrrolizidine alkaloids from transannular iodoaminations: application to the asymmetric syntheses of (-)-hyacinthacine A1, (-)-7a-epi-hyacinthacine A1, (-)-hyacinthacine A2, and (-)-1-epi-alexine.
由: Brock, E, et al.
出版: (2013)

Hepatotoxicity of Pyrrolizidine Alkaloids
由: Manuela G Neuman, et al.
出版: (2015-11-01)

Asymmetric syntheses of (-)-isoretronecanol and (-)-trachelantamidine
由: Brambilla, M, et al.
出版: (2014)

Asymmetric synthesis of pyrrolizidines, indolizidines and quinolizidines via a double reductive cyclisation protocol
由: Davies, S, et al.
出版: (2017)

Asymmetric syntheses of (- )-hastanecine, (- )-turneforcidine and (- )-platynecine
由: Davies, S, et al.
出版: (2016)

Hepatotoxicity of Pyrrolizidine Alkaloid Compound Intermedine: Comparison with Other Pyrrolizidine Alkaloids and Its Toxicological Mechanism
由: Ziqi Wang, et al.
出版: (2021-11-01)

Asymmetric syntheses of the homalium alkaloids (-)-(S,S)-homaline and (-)-(R,R)-hopromine.
由: Davies, S, et al.
出版: (2012)

Asymmetric synthesis of the tetraponerine alkaloids
由: Davies, S, et al.
出版: (2017)

The Hancock alkaloids (-)-cuspareine, (-)-galipinine, (-)-galipeine, and (-)-angustureine: asymmetric syntheses and corrected 1H and 13C NMR data
由: Davies, S, et al.
出版: (2018)

Flexible strategy for the synthesis of pyrrolizidine alkaloids.
由: Donohoe, T, et al.
出版: (2008)

Pyrrolizidine Alkaloids in Food on the Italian Market
由: Mariantonietta Peloso, et al.
出版: (2023-07-01)

Pyrrolizidine Alkaloids: the underestimated natural toxicants
由: Ana, et al.
出版: (2022-04-01)

Characterization and Lifetime Dietary Risk Assessment of Eighteen Pyrrolizidine Alkaloids and Pyrrolizidine Alkaloid N-Oxides in New Zealand Honey
由: Andrew J. Pearson, et al.
出版: (2021-11-01)

Pyrrolizidine alkaloids from Heliotropium transoxanum Bunge
由: M. R. Delnavazi, et al.
出版: (2016-02-01)

Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis
由: Robertson, J, et al.
出版: (2016)

Isolation of the pyrrolizidine alkaloid 1-epialexine from Castanospermum australe
由: Jones, L, et al.
出版: (2010)

Asymmetric synthesis of polyhydroxylated pyrrolizidines via transannular iodoamination with concomitant N-debenzylation.
由: Brock, E, et al.
出版: (2011)

Pyrrolizidine Alkaloid Extraction and Analysis: Recent Updates
由: Sarah F. Al-Subaie, et al.
出版: (2022-11-01)

Asymmetric syntheses of the pseudodistomin alkaloids
由: Zimmer, D
出版: (2018)

ENANTIOSPECIFIC SYNTHESES OF INTERMEDIATES IN THE TOTAL SYNTHESIS OF PSEUDOMONIC ACIDS
由: Fleet, G, et al.
出版: (1982)

Pyrrolizidine alkaloids: An update on their metabolism and hepatotoxicity mechanism
由: Jie Xu, et al.
出版: (2019-12-01)

Pyrrolizidine alkaloids of senecio sp from Peru
由: Liliana Ruiz Vásquez and Matías Reina Artiles, et al.
出版: (2011-01-01)

Scientific Opinion on Pyrrolizidine alkaloids in food and feed
由: EFSA Panel on Contaminants in the Food Chain (CONTAM)
出版: (2011-11-01)

Tolerating Toxins: Grasshoppers that Feast on Pyrrolizidine Alkaloids §
由: Catherine E. Housecroft
出版: (2018-03-01)

Enantiospecific alkylations of alanine
由: Alonso, F, et al.
出版: (1998)

Asymmetric syntheses of fagomine and its stereoisomers
由: Davies, S, et al.
出版: (2019)

CASUARINE - A VERY HIGHLY OXYGENATED PYRROLIZIDINE ALKALOID
由: Nash, R, et al.
出版: (1994)

Enantiospecific stereodivergent synthesis of trans- and cis-N(2),3-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinolines.
由: Coote, S, et al.
出版: (2010)

Pyrrolizidine alkaloids from Bulgarian species of the genus Senecio
由: Kostova Nadezhda, et al.
出版: (2006-01-01)

Dietary exposure assessment to pyrrolizidine alkaloids in the European population
由: European Food Safety Authority (EFSA)
出版: (2016-08-01)

Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera)
由: Ivette M. Menéndez-Perdomo, et al.
出版: (2023-02-01)

Total synthesis of the pyrrolizidine alkaloid natural product NP25302
由: Stevens, K, et al.
出版: (2011)

In vitro-in silico study on the influence of dose, fraction bioactivated and endpoint used on the relative potency value of pyrrolizidine alkaloid N-oxides compared to parent pyrrolizidine alkaloids
由: Yasser Alhejji, et al.
出版: (2024-01-01)

Extracting and Analyzing Pyrrolizidine Alkaloids in Medicinal Plants: A Review
由: Thomas Kopp, et al.
出版: (2020-05-01)

Pyrrolizidine alkaloids and health risk of three Boraginaceae used in TCM
由: Ke Zan, et al.
出版: (2023-03-01)