Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages.

In yeast and metazoa, structural maintenance of chromosome (SMC) complexes play key roles in chromosome segregation, architecture and DNA repair. The main function of the cohesin complex is to hold replicated sister chromatids together until segregation at anaphase, which is dependent on proteolytic...

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Bibliographic Details
Main Authors: Gluenz, E, Sharma, R, Carrington, M, Gull, K
Format: Journal article
Language:English
Published: 2008