A method for producing monoclonal antibodies to human T-cell-receptor beta-chain variable regions.

Study of the T-cell repertoire in humans has been hampered by the lack of monoclonal antibodies (mAbs) to the T-cell receptor (TCR) variable region (V) gene products. We describe a method for producing mAbs to the human TCR beta-chain V (V beta) gene products in which mice were immunized with a rat...

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Detalhes bibliográficos
Main Authors: Callan, M, Reyburn, H, Bowness, P, Ottenhoff, T, Engel, I, Klausner, R, Bell, J, McMichael, A
Formato: Journal article
Idioma:English
Publicado em: 1993