Coupling of Ca(2+) microdomains to spatially and temporally distinct cellular responses by the tyrosine kinase Syk.

Communication between the cell surface and the nucleus is essential for regulated gene expression. In neurons, Ca(2+)-dependent gene transcription is sensitive to local Ca(2+) entry. In immune cells, excitation-transcription coupling is thought to involve global Ca(2+) signals. Here, we show that in...

詳細記述

書誌詳細
主要な著者: Ng, S, Nelson, C, Parekh, A
フォーマット: Journal article
言語:English
出版事項: 2009