The alarmin IL-33 promotes regulatory T-cell function in the intestine.

FOXP3(+) regulatory T cells (Treg cells) are abundant in the intestine, where they prevent dysregulated inflammatory responses to self and environmental stimuli. It is now appreciated that Treg cells acquire tissue-specific adaptations that facilitate their survival and function; however, key host f...

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Bibliographic Details
Main Authors: Schiering, C, Krausgruber, T, Chomka, A, Fröhlich, A, Adelmann, K, Wohlfert, E, Pott, J, Griseri, T, Bollrath, J, Hegazy, A, Harrison, O, Owens, B, Löhning, M, Belkaid, Y, Fallon, P, Powrie, F
Format: Journal article
Language:English
Published: 2014