Ischemic preconditioning prevents endothelial injury and systemic neutrophil activation during ischemia-reperfusion in humans in vivo.

BACKGROUND: Endothelial dysfunction leading to neutrophil infiltration of tissues has been implicated in tissue injury caused by ischemia-reperfusion (IR). Tissue injury during IR can be reduced by prior ischemic preconditioning (IPC). In humans, it is unclear whether endothelial dysfunction occurs...

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Bibliographic Details
Main Authors: Kharbanda, R, Peters, M, Walton, B, Kattenhorn, M, Mullen, M, Klein, N, Vallance, P, Deanfield, J, MacAllister, R
Format: Journal article
Language:English
Published: 2001