Ischemic preconditioning prevents endothelial injury and systemic neutrophil activation during ischemia-reperfusion in humans in vivo.
BACKGROUND: Endothelial dysfunction leading to neutrophil infiltration of tissues has been implicated in tissue injury caused by ischemia-reperfusion (IR). Tissue injury during IR can be reduced by prior ischemic preconditioning (IPC). In humans, it is unclear whether endothelial dysfunction occurs...
Main Authors: | Kharbanda, R, Peters, M, Walton, B, Kattenhorn, M, Mullen, M, Klein, N, Vallance, P, Deanfield, J, MacAllister, R |
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Format: | Journal article |
Language: | English |
Published: |
2001
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