Definition of the viral targets of protective HIV-1-specific T cell responses.

BACKGROUND: The efficacy of the CTL component of a future HIV-1 vaccine will depend on the induction of responses with the most potent antiviral activity and broad HLA class I restriction. However, current HIV vaccine designs are largely based on viral sequence alignments only, not incorporating exp...

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Bibliographic Details
Main Authors: Mothe, B, Llano, A, Ibarrondo, J, Daniels, M, Miranda, C, Zamarreño, J, Bach, V, Zuniga, R, Pérez-Álvarez, S, Berger, C, Puertas, M, Martinez-Picado, J, Rolland, M, Farfan, M, Szinger, J, Hildebrand, W, Yang, O, Sanchez-Merino, V, Brumme, C, Brumme, Z, Heckerman, D, Allen, T, Mullins, J, Gómez, G, Goulder, P
Format: Journal article
Language:English
Published: 2011