Deletion of AMPA receptor GluA1 subunit gene (Gria1) causes circadian rhythm disruption and aberrant responses to environmental cues

Dysfunction of the glutamate α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor GluA1 subunit and deficits in synaptic plasticity are implicated in schizophrenia and sleep and circadian rhythm disruption. To investigate the role of GluA1 in circadian and sleep behaviour, we used wh...

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Detalles Bibliográficos
Main Authors: Ang, G, Brown, LA, Tam, SKE, Davies, KE, Foster, RG, Harrison, PJ, Sprengel, R, Vyazovskiy, VV, Oliver, PL, Bannerman, DM, Peirson, SN
Formato: Journal article
Idioma:English
Publicado: Springer Nature 2021