Identification of the cellular and molecular mechanisms of IL-23 driven intestinal inflammation

<p>IL-23 is an essential mediator of chronic intestinal inflammation in experimental models of colitis. Polymorphisms in the IL23R locus are associated with IBD susceptibility in humans. The biological activity of IL-23 has been linked to Th17 cells but little is known about the cellular and m...

Full description

Bibliographic Details
Main Author: Schiering, C
Other Authors: Powrie, F
Format: Thesis
Language:English
Published: 2013
Subjects: