Identification of the cellular and molecular mechanisms of IL-23 driven intestinal inflammation
<p>IL-23 is an essential mediator of chronic intestinal inflammation in experimental models of colitis. Polymorphisms in the IL23R locus are associated with IBD susceptibility in humans. The biological activity of IL-23 has been linked to Th17 cells but little is known about the cellular and m...
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Format: | Thesis |
Language: | English |
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2013
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