Mage-3 and influenza-matrix peptide-specific cytotoxic T cells are inducible in terminal stage HLA-A2.1+ melanoma patients by mature monocyte-derived dendritic cells.

Mage-3 and influenza-matrix peptide-specific cytotoxic T cells are inducible in terminal stage HLA-A2.1+ melanoma patients by mature monocyte-derived dendritic cells.

Dendritic cell (DC) vaccination, albeit still in an early stage, is a promising strategy to induce immunity to cancer. We explored whether DC can expand Ag-specific CD8+ T cells even in far-advanced stage IV melanoma patients. We found that three to five biweekly vaccinations of mature, monocyte-der...

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Bibliographic Details
Main Authors: Schuler-Thurner, B, Dieckmann, D, Keikavoussi, P, Bender, A, Maczek, C, Jonuleit, H, Röder, C, Haendle, I, Leisgang, W, Dunbar, R, Cerundolo, V, von Den Driesch, P, Knop, J, Bröcker, E, Enk, A, Kämpgen, E, Schuler, G
Format: Journal article
Language:English
Published: 2000

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