Intravenous immunoglobulins promote skin allograft acceptance by triggering functional activation of CD4+Foxp3+ T cells.

BACKGROUND: Intravenous immunoglobulins (IVIg) therapy is effective as a treatment for T-cell-mediated immune diseases, but whether and how IVIg suppress allogeneic T-cell responses is largely unknown. METHODS: In vitro, human CD4(+), CD4(+)CD25(-), or CD4(+)CD25(+) T cells were stimulated with all...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Tha-In, T, Metselaar, H, Bushell, A, Kwekkeboom, J, Wood, K
التنسيق: Journal article
اللغة:English
منشور في: 2010