Intravenous immunoglobulins promote skin allograft acceptance by triggering functional activation of CD4+Foxp3+ T cells.
BACKGROUND: Intravenous immunoglobulins (IVIg) therapy is effective as a treatment for T-cell-mediated immune diseases, but whether and how IVIg suppress allogeneic T-cell responses is largely unknown. METHODS: In vitro, human CD4(+), CD4(+)CD25(-), or CD4(+)CD25(+) T cells were stimulated with all...
Asıl Yazarlar: | Tha-In, T, Metselaar, H, Bushell, A, Kwekkeboom, J, Wood, K |
---|---|
Materyal Türü: | Journal article |
Dil: | English |
Baskı/Yayın Bilgisi: |
2010
|
Benzer Materyaller
-
Direct functional activation of CD4+CD25+Foxp3+T cells by intravenous immunoglobulins promotes skin allograft acceptance.
Yazar:: Tha-In, T, ve diğerleri
Baskı/Yayın Bilgisi: (2008) -
INTRAVENOUS IMMUNOGLOBULINS INDUCE DIRECT FUNCTIONAL ACTIVATION OF CD4+CD25+FOXP3+T CELLS: A VALUABLE TOOL AFTER TRANSPLANTATION.
Yazar:: Tha-In, T, ve diğerleri
Baskı/Yayın Bilgisi: (2008) -
CD25+CD4+ regulatory T cells develop in mice not only during spontaneous acceptance of liver allografts but also after acute allograft rejection.
Yazar:: Steger, U, ve diğerleri
Baskı/Yayın Bilgisi: (2006) -
Interferon-gamma conditioning ex vivo generates CD25+CD62L+Foxp3+ regulatory T cells that prevent allograft rejection: potential avenues for cellular therapy.
Yazar:: Feng, G, ve diğerleri
Baskı/Yayın Bilgisi: (2008) -
GITR ligation blocks allograft protection by induced CD25+CD4+ regulatory T cells without enhancing effector T-cell function.
Yazar:: Bushell, A, ve diğerleri
Baskı/Yayın Bilgisi: (2007)