Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations.

Even though hematopoietic stem cell (HSC) dysfunction is presumed in myelodysplastic syndrome (MDS), the exact nature of quantitative and qualitative alterations is unknown. We conducted a study of phenotypic and molecular alterations in highly fractionated stem and progenitor populations in a varie...

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Bibliographic Details
Main Authors:	Will, B, Zhou, L, Vogler, T, Ben-Neriah, S, Schinke, C, Tamari, R, Yu, Y, Bhagat, T, Bhattacharyya, S, Barreyro, L, Heuck, C, Mo, Y, Parekh, S, McMahon, C, Pellagatti, A, Boultwood, J, Montagna, C, Silverman, L, Maciejewski, J, Greally, J, Ye, B, List, A, Steidl, C, Steidl, U, Verma, A
Format:	Journal article
Language:	English
Published:	2012

Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations.

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