Exploring the roles of Mus81-Eme1/Mms4 at perturbed replication forks.

Cells of all living organisms have evolved complex mechanisms that serve to stabilise, repair and restart stalled, blocked and broken replication forks. The heterodimeric Mus81-Eme1/Mms4 structure-specific endonuclease appears to play an important role(s) in homologous recombination-mediated process...

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Détails bibliographiques
Auteurs principaux: Osman, F, Whitby, M
Format: Journal article
Langue:English
Publié: 2007