Modelling perspectives on the intestinal crypt, a canonical system for growth, mechanics and remodelling

The intestinal epithelium is crucial to maintaining a healthy gut. Central to this are the crypts of Lieberkühn, which coordinate the rapid self-renewal of the epithelium to protect the small intestine and colon during digestion. Further, mutations in crypt cells may initiate colorectal cancer. It i...

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Bibliographic Details
Main Authors: Almet, A, Maini, P, Moulton, D, Byrne, H
Format: Journal article
Language:English
Published: Elsevier 2020