Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria

Transcription in bacteria is controlled by multiple molecular mechanisms that precisely regulate gene expression. It has been recently shown that initial RNA synthesis by the bacterial RNA polymerase (RNAP) is interrupted by pauses; however, the pausing determinants and the relationship of pausing w...

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Bibliographic Details
Main Authors: Dulin, D, Bauer, D, Malinen, A, Bakermans, J, Kaller, M, Morichaud, Z, Petushkov, I, Depken, M, Brodolin, K, Kulbachinskiy, A, Kapanidis, A
Format: Journal article
Published: Nature Publishing Group 2018