Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells.

We have described a murine model of IBD that was induced in C.B-17 scid mice by transfer of the CD45RBhi subpopulation of CD4+ T cells from normal BALB/c mice and could be prevented by cotransfer of the CD45RBlo CD4+ T cell subset. Here we have dissected the mechanism of pathogenesis of IBD in this...

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Xehetasun bibliografikoak
Egile Nagusiak: Powrie, F, Leach, M, Mauze, S, Menon, S, Caddle, L, Coffman, R
Formatua: Journal article
Hizkuntza:English
Argitaratua: 1994